NITRIC OXIDE (NO) AND DUCHENNE MUSCULAR DYSTROPHY: NO WAY TO GO?

Nitric Oxide (NO) and Duchenne Muscular Dystrophy: NO Way to Go?

The discordance between pre-clinical success and clinical failure of treatment options for Duchenne Muscular Dystrophy (DMD) is significant.The termination of clinical trials investigating the phosphodiesterase inhibitors, sildenafil and tadalafil (which prolong the second messenger molecule of nitric oxide (NO) signaling), are prime examples of th

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Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

Skeletal muscle conveys the beneficial effects of physical exercise but due to its heterogeneity, studying the effects of exercise TENS/EMS Units on muscle fibres is challenging.Here, the authors carry out proteomic analysis of myofibres from freeze-dried muscle biopsies, show fibre-type specific changes Rocker Recliner in response to exercise, and

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Identification and evaluation of high-performing advanced germplasm of rice through morphological and breeding value analysis

Abstract Principal component analysis (PCA) and breeding value analysis (BV) were used to discover genotypes with better features for future breeding efforts.This research included a thorough analysis of the 300 exceptional rice germplasms provided by the Bangladesh Rice Research In (BRRI) and the International Rice Research Institute (IRRI).In the

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